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KMID : 0604020160310020134
Korean Journal of Critical Care Medicine
2016 Volume.31 No. 2 p.134 ~ p.139
Fatal Intracranial Hemorrhage in a Patient with Disseminated Intravascular Coagulation associated with Sepsis
Baek Hyun-Jin

Lee Doo-Hyuk
Han Kyu-Hyung
Kim Young-Min
Kim Hyun-beom
Cho Byeong-Wook
Lee In-Kuk
Choi Kang-Hyun
Yong Ho-Jin
Hong Goo-Hyeon
Abstract
In critically ill patients, disseminated intravascular coagulation (DIC) is a common and fatal hematological disorder. DIC is a physiological response to a variety of underlying stimuli that provoke generalized activation of the hemostatic mechanism and is common in septic patients and those with hematological or non-hematological malignant neoplasms. Bleeding is a common clinical feature, and diffuse or multiple-site mucocutaneous bleeding, such as petechia, ecchymosis and hemorrhage from gastrointestinal tract, is often seen. A 58-year-old male was recently diagnosed with intracranial hemorrhage (ICH) caused by DIC associated with sepsis. Mortality of ICH caused by DIC is very high because the underlying condition cannot be quickly treated. Awareness of the possibility of DIC developing in a critically ill patient and the need for immediate initiation of plasma or platelet replacement therapy are important. To the best of our knowledge, this is the first reported case of intracranial hemorrhage in a Korean patient with DIC associated with sepsis.
KEYWORD
disseminated intravascular coagulation, intracranial hemorrhage, sepsis
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